Beneficial effect of ezetimibe-atorvastatin combination therapy in patients with a mutation in ABCG5 or ABCG8 gene

Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.

The ATP binding cassette transporters ABCG5 (G5) and ABCG8 (G8) limit the accumulation of neutral sterols by restricting sterol uptake from the intestine and promoting sterol excretion into bile. Humans and mice lacking G5 and G8 (G5G8-/-) accumulate plant sterols in the blood and tissues. However, despite impaired biliary cholesterol secretion, plasma and liver cholesterol levels are lower in ...

evaluation of fat atrophy in patients with dermis fat graft of orbit by ct-scan

چکیده ندارد.

assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.

چکیده ندارد.

The Effect of Combined Training on ABCG5 and ABCG8 in Coronary Artery Bypass Graft Patients

Aims Coronary heart disease is one of the leading causes of mortality in modern societies. The disease is associated with the lack of physical activity and the expression of some genes involved in blood cholesterol transportation. Adenosine triphosphate (ATP)-binding cassette transporters G5/G8) ABCG5 and ABCG8) is the expression of adenosine triphosphate-dependent box protein genes 5 and 8, a ...

Atorvastatin in combination with ezetimibe and carotid atherosclerosis.